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101 Best California Medical Device Startups

This article showcases our top picks for the best California based Medical Device companies. These startups and companies are taking a variety of approaches to innovating the Medical Device industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

Top California Medical Device Startups

Data sourced from Crunchbase and SemRush.

Imperative Care

Imperative Care

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Imperative Care is singularly dedicated to finding meaningful answers to unsolved problems in stroke.

AliveCor

AliveCor

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AliveCor is a FDA-cleared mobile heart solution that helps save lives, save money, and brings healthcare into the 21st century.

AliveCor

Cytek Biosciences

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Cytek Biosciences is a manufacturer and supplier of flow cytometry products and services.

AliveCor

Grail

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Grail develops a pan-cancer screening test designed to detect cancers at an early stage.

AliveCor

Osso VR

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Osso VR is a training and assessment platform focused on surgical virtual reality.

AliveCor

NexHealth

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NexHealth is a real-time patient booking platform for people, their doctors, and healthcare developers.

AliveCor

Dexcom

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Dexcom develops, manufactures, and distributes continuous glucose monitoring systems for diabetes management.

AliveCor

Exo

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Exo is a medical device startup which develops handheld ultrasound devices and AI for imaging and therapeutic applications.

AliveCor

Lark

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Lark is a digital health startup that provides virtual care through AI coaching, smart devices, and tele-monitoring.

AliveCor

NeuSpera Medical

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NeuSpera, formerly known as Vivonda Medical, is developing injectable neuromodulation devices, so called “electroceuticals

AliveCor

NeuroPace

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NeuroPace develops and markets implantable devices for the treatment of neurological disorders.

AliveCor

Velano Vascular

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Velano Vascular is a medical device innovator committed to enhancing both inpatient blood collection and vascular access

AliveCor

Medable

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Medable is transforming clinical research and predictive medicine by creating a platform powered by patient generated data.

AliveCor

Eyenuk, Inc.

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Eyenuk, Inc. is a global digital health company and leader in real-world AI eye screening for autonomous disease detection

AliveCor

Viz

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Viz is a medical imaging company that helps optimize emergency treatment using deep learning technology.

AliveCor

iRhythm Technologies

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iRhythm Technologies provides diagnostic monitoring solutions that facilitate the early diagnosis and treatment of cardiac arrhythmia.

AliveCor

Premise Data

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Premise is a data and analytics platform powered by a global network of on-the-ground contributors, data science, and machine learning.

AliveCor

RayzeBio

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RayzeBio is a pharmaceuticals company that develops targeted radiopharmaceutical drugs for cancer.

AliveCor

Synchron

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Synchron is a bioelectronics medicine company that develops neuromodulation solutions for previously-untreatable nervous system conditions.

AliveCor

PROCEPT BioRobotics

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PROCEPT BioRobotics is a surgical robotics company enabling better patient care by developing transformative solutions in urology.

AliveCor

Eargo

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Eargo makes direct-to-consumer hearing aids, allowing customers to access help for their hearing loss from their homes.

AliveCor

Ancora Heart

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Ancora Heart is dedicated to helping people with heart failure feel better and live longer.

AliveCor

Cue

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Cue helps users track their health at the molecular level, revealing the interplay of activity, food, and sleep.

AliveCor

SetPoint Medical

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SetPoint Medical treats patients with debilitating inflammatory diseases using proprietary implantable bioelectronic devices.

AliveCor

Eko

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Eko develops FDA approved, AI-powered heart sound and EKG sensors for heart disease monitoring.

AliveCor

ResMed

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ResMed provides medical equipment for treating, diagnosing, and managing sleep-disordered breathing and other respiratory disorders.

AliveCor

Qualio

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Qualio is a quality management system helping life sciences companies bring quality products to the market.

AliveCor

Bigfoot Biomedical

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Bigfoot Biomedical is a medical device company changing diabetes care for people with insulin-requiring diabetes.

AliveCor

VitalConnect

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VitalConnect is a wearable biosensor technology for wireless hospital and remote patient monitoring.

AliveCor

RxSight

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RxSight is a medical device company that offers an intraocular lens and cataract surgery solutions.

AliveCor

Pulse Biosciences

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Pulse Biosciences is a medical device company that engages in the research and development, and commercialization of CellFX system.

AliveCor

Acutus Medical

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Acutus Medical develops medical technologies to treat complex cardiac arrhythmia.

AliveCor

Tempo Automation

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Tempo Automation is the world’s first AI-driven Smart Factory designed for low volume, high complexity PBCA production.

AliveCor

Caption Health

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Caption Health is a medical company that uses artificial intelligence (AI) to interpret ultrasound exams.

AliveCor

RefleXion Medical

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RefleXion Medical is a developer of biologically-guided radiotherapy systems for patients with cancer.

AliveCor

Auris Health

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Auris Health engages in the development of robotics technology for medical applications.

AliveCor

Arterys

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Arterys is a medical imaging platform to deliver clinical AI products over the internet.

AliveCor

Avail Medsystems

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Avail Medsystems is a medical technology company that develops telemedicine software for the procedure room.

AliveCor

Truvian Sciences

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Truvian disrupts the blood-testing industry by developing an automated diagnostic system that provides lab-accurate results.

AliveCor

Eureka Therapeutics

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Eureka Therapeutics is a biotechnology company focusing on immunotherapies for the treatment of cancer.

AliveCor

ReShape Lifesciences

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ReShape Lifesciencesis a developer of minimally invasive medical devices to treat obesity and metabolic diseases.

AliveCor

Silk Road Medical

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Silk Road Medical provides research and development services of medical devices for neurovascular diseases.

AliveCor

Earlens Corporation

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Earlens is a privately held medical technology company transforming the hearing experience with the only direct sound delivery system.

AliveCor

Whisper

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Whisper develops AI-enabled, updateable hearing aids for people with hearing loss.

AliveCor

Ceribell

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Ceribell focuses on making electroencephalography (EEG) widely accessible, more efficient, and more cost-effective.

AliveCor

TRACON Pharmaceuticals

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TRACON Pharmaceuticals is a biopharmaceutical company focused on developing targeted therapies for cancer and macular degeneration.

AliveCor

Curative

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Curative is a leader in on-demand public health programs and infrastructure. Building a healthier tomorrow, together.

AliveCor

RapidAI

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RapidAI empowers clinicians to make faster, more accurate diagnostic and treatment decisions for stroke and aneurysm patients.

AliveCor

Outset Medical

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Outset Medical is a pioneering medical technology company that manufactures medical equipment.

AliveCor

Inari Medical

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Inari Medical is a medical device company that develops devices for the interventional treatment of cardiovascular diseases.

AliveCor

Enlitic

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Enlitic builds AI deep learning products to streamline radiologists’ workflows and improve healthcare diagnosis.

AliveCor

Second Sight

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Second Sight manufactures and markets implantable visual prosthetics to enable blind individuals to achieve greater independence.

AliveCor

NovaSignal

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NovaSignal is a medical technology company commercializing a robotic cerebral ultrasound system.

AliveCor

ChemoCentryx

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ChemoCentryx develops orally administered small molecule therapeutics that target chemokine receptors and related chemo-attractants.

AliveCor

Tandem Diabetes Care

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Tandem Diabetes Care develops medical devices for the treatment of diabetes offering diabetic insulin pumps for adults and children.

AliveCor

Vaxart

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Vaxart is a biotechnology company that develops vaccine technology for the treatment of infectious diseases.

AliveCor

DJO Global

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DJO Global is a manufacturer and distributor of medical devices for musculoskeletal health, vascular health, and pain management.

AliveCor

Zap Surgical Systems

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ZAP Surgical Systems designs and manufactures the ZAP-X® radiosurgery platform.

AliveCor

Neuro42

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Neuro42 is developing and commercializing advanced MRI technology for diagnosis and image-guided interventions.

AliveCor

ClearPoint Neuro

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ClearPoint Neuro is a platform neuro company that enables therapy for neuro disorders with pinpoint accuracy.

AliveCor

Pulmonx

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Pulmonx provides minimally-invasive medical devices and technologies for the diagnosis and treatment of pulmonary disorders.

AliveCor

Intarcia Therapeutics

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Intarcia Therapeutics develops therapies for diseases that require long-term chronic treatment.

AliveCor

Minerva Surgical

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Minerva Surgical is a medical device start-up company developing medical devices for women’s healthcare.

AliveCor

Promaxo

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Promaxo is commercializing customer-centric MRI systems and robotic guidance tools for live diagnosis and treatment in a physician’s office.

AliveCor

Dascena

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Dascena develops machine learning algorithms to enable early disease intervention and improve care outcomes for patients.

AliveCor

Unchained Labs

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Unchained Labs is a developer of life science biologics tools designed to help researchers break free from tools that just don’t cut it.

AliveCor

Fluxergy

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Fluxergy is a biotechnology company that offers point-of-care testing, PCR, and medical diagnostics.

AliveCor

Alphatec Spine

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Alphatec Spine is a medical device company developing products and treatments for spine disorders.

AliveCor

Shockwave Medical

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Shockwave Medical is developing the Lithoplasty™ family of balloon dilatation catheters that incorporate tiny lithotripsy electrodes.

AliveCor

Mira

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The first FDA and CE registered comprehensive women’s health and chronic disease monitoring platform with 99% of accuracy

AliveCor

Catalyst Biosciences

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Catalyst Biosciences is a drug R&D company creating catalytic biopharmaceutical products based on engineered human proteases.

AliveCor

Onera Health

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Onera Health is a world-leading research center for nano electronics and digital technology company.

AliveCor

Profusa

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PROFUSA is a medical devices company creating tissue-integrated sensors for chronic disease management and healthy living.

AliveCor

iHealth Labs

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iHealth offers cloud-based, personal healthcare products for individuals of all ages to take a more active role in managing their health.

AliveCor

InTouch Health

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InTouch Health is the leader in Acute Care Telemedicine solutions.

AliveCor

DiCE Molecules

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DiCE Molecules is a developer of transformative platform for the discovery of novel small molecules.

AliveCor

Element Science

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Element Science is a medical device and digital health start-up that develops lifesaving wearable solutions.

AliveCor

Intuity Medical

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Intuity Medical develops blood glucose monitoring systems for diabetes management.

AliveCor

Potrero Medical

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Potrero Medical is a predictive health company that is developing the next generation of smart sensors and artificial intelligence.

AliveCor

HydraFacial

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HydraFacial is an FDA registered manufacturer of advanced aesthetic technologies and products.

AliveCor

HALO Diagnostics

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HALO Diagnostics is a rapid growth technology company that creates life-changing patient insights and outcomes in radiology.

AliveCor

Evolve Biosystems

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Evolve Biosystems specializes in providing microbiome-based products designed to develop, restore, and maintain.

AliveCor

Sitka

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Sitka is a customizable video software platform that connects primary care providers to the virtual specialty provider network.

AliveCor

Dynavax Technologies

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Dynavax Technologies is a biopharmaceutical company discovering and developing novel products to prevent and treat infectious diseases.

AliveCor

Ensurge Micropower

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Solid-state microbatteries for wearables and connected sensors

AliveCor

INBRACE

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Swift Health Systems is a stealth stage start-up medical device company, developing INBRACE.

AliveCor

Tioga Medical

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Tioga Medical is a healthcare company.

AliveCor

Biolinq

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Biolinq develops a wearable biosensor platform that is capable of measuring blood level information.

AliveCor

Halo Neuroscience

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Halo Neuroscience is a neurotech company focused on using electrical neurostimulation to unlock human performance and treat human disease

AliveCor

VoxelCloud

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VoxelCloud provides automated medical image analysis services and diagnosis assistance based on AI and cloud computing technologies.

AliveCor

NuVasive

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NuVasive is a medical device company developing minimally disruptive surgical products and procedurally integrated solutions for the spine.

AliveCor

Hound Labs

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Hound Labs is a breath technology company that has developed ultra-sensitive technology for non-invasive breath measurement.

AliveCor

Gauss Surgical

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Gauss Surgical is a med-tech company that develops a vision-based platform for accurate and real-time measurement of surgical blood loss.

AliveCor

Q’Apel Medical

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Q’Apel Medical designs access device technology for neurovascular interventions and unmet clinical needs.

AliveCor

Axonics Modulation Technologies

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Axonics Modulation Technologies is a pre-revenue company developing novel implantable neuromodulation.

AliveCor

Alveo Technologies

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Alveo is a pre-clinical stage medical diagnostics company .

AliveCor

Echo

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Echo is a provider of an automated microscope intended for biological research and pathologies.

AliveCor

Demetrix

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Demetrix is a biotechnology company that manufactures natural medicines using synthesis biology to make medical drugs.

AliveCor

EndoGastric Solutions

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EGS manufactures EsophyX technology is used to reconstruct the gastroesophageal valve in the TIF 2.0 procedure.

AliveCor

Avita Medical

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Avita is a medical company that specializes in regenerative medicine, chronic wounds, and plastic surgery.

AliveCor

ROAM

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ROAM is a San Francisco-based robotics company that is developing mobility through is powered orthotics, known as exoskeletons.

Written by Warren Tesla

My name is Tesla and I am the pseudonym used by The Stratup Pill's broad writing team.

About me: Founder, CEO, CTO, CFO, CMO, CISO, Director, Head of the Board, Head of the oversight board, Executive, Legal Council, Head of Hiring, HR Manager, Consultant.

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