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101 Best Minnesota Medical Device Startups

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This article showcases our top picks for the best Minnesota based Medical Device companies. These startups and companies are taking a variety of approaches to innovating the Medical Device industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

Top Minnesota Medical Device Startups

Data sourced from Crunchbase and SemRush.

Medtronic

Medtronic

Crunchbase Website Twitter Facebook Linkedin

Medtronic develops and manufactures medical device technologies and therapies to treat chronic diseases worldwide.

CVRx

CVRx

Crunchbase Website Twitter Facebook Linkedin

CVRx is a medical device company developing implantable technology for the treatment of high blood pressure.

CVRx

Miromatrix Medical

Crunchbase Website Twitter Facebook Linkedin

Miromatrix Medical is engaged in the development of fully biological human organs and organ-derived biological products.

CVRx

Inspire Medical Systems

Crunchbase Website Twitter Facebook Linkedin

Inspire Medical Systems develops implantable therapeutic devices for the treatment of obstructive sleep apnea.

CVRx

HistoSonics

Crunchbase Website Twitter Facebook Linkedin

HistoSonics specializes in developing medical devices, interventional radiology, and surgical robotics.

CVRx

Monteris Medical

Crunchbase Website Twitter Facebook Linkedin

Monteris Medical is a medical device venture that develops new technologies for the treatment of cancer.

CVRx

MIVI Neuroscience

Crunchbase Website Twitter Facebook Linkedin

MIVI Neuroscience focuses on developing and commercializing clinical solutions for neurointerventional procedures.

CVRx

Nuvaira

Crunchbase Website Twitter Facebook Linkedin

Nuvaira is a new alternative COPD treatment option that specializes in developing devices for treating lung diseases.

CVRx

Respicardia

Crunchbase Website Twitter Facebook Linkedin

Respicardia develops implantable therapies to improve respiratory and cardiovascular health.

CVRx

Aria CV

Crunchbase Website Twitter Facebook Linkedin

Aria CV is developing a medical device designed to improve the lives of patients living with the disease of pulmonary hypertension.

CVRx

Conventus Orthopaedics

Crunchbase Website Twitter Facebook Linkedin

Conventus Orthopaedics is a provider of a range of orthopedic and sports medicine services.

CVRx

EnteroMedics

Crunchbase Website Twitter Facebook Linkedin

EnteroMedics® Inc. (NASDAQ: ETRM) is the developer of in-class weight loss treatments for obesity and obesity related risk factors.

CVRx

4C Medical Technologies

Crunchbase Website Twitter Facebook Linkedin

4C Medical Technologies is a medical device company that develops minimally invasive therapies for structural heart disease.

CVRx

Pops Diabetes Care

Crunchbase Website Twitter Facebook Linkedin

Pops Diabetes Care offers a virtual healthcare platform to enable people to self-manage diabetes through consumer-centric sensors.

CVRx

Cardiovascular Systems

Crunchbase Website Twitter Facebook Linkedin

Cardiovascular Systems develops and markets medical devices for the treatment of cardiovascular disease.

CVRx

Biothera

Crunchbase Website Twitter Facebook Linkedin

Biothera is a biotechnology company developing natural gluco polysaccharides that engage and direct natural innate immune systems.

CVRx

NeoChord

Crunchbase Website Twitter Facebook Linkedin

NeoChord is a medical device company that develops devices that allow mitral valve repair to be performed on a beating heart.

CVRx

CardiaLen

Crunchbase Website Twitter Facebook Linkedin

CardiaLen develops and commercializes pain-free cardioversion therapies for atrial fibrillation.

CVRx

ABS

Crunchbase Website Twitter Facebook Linkedin

ABS designs and develops minimally-invasive technology that focuses on relieving pain in the knee.

CVRx

Minnetronix

Crunchbase Website Twitter Facebook Linkedin

We are a medical technology and innovation company with deep expertise in electronic and electromechanical devices.

CVRx

Spineology

Crunchbase Website Twitter Facebook Linkedin

Spineology provides anatomy-conserving spine surgery technology solutions.

CVRx

NxThera

Crunchbase Website Twitter Facebook Linkedin

NxThera develops medical technologies to treat a variety of endourology conditions, including BPH.

CVRx

Healthsense

Crunchbase Website Twitter Facebook Linkedin

Healthsense is a provider of aging services technology, offering technology-enabled care solutions for the senior care continuum.

CVRx

Cardionomic

Crunchbase Website Twitter Facebook Linkedin

Cardionomic is a medical device developer that treats reduced cardiac output.

CVRx

ShiraTronics

Crunchbase Website Twitter Facebook Linkedin

ShiraTronics is in the early stages of developing new innovative therapies to combat debilitating migraine headache.

CVRx

IMRIS Inc.

Crunchbase Website Twitter Facebook Linkedin

IMRIS provides an image-guided therapy environment, facilitating timely information to clinicians to use during surgical procedures.

CVRx

Abilitech Medical

Crunchbase Website Twitter Facebook Linkedin

Abilitech Medical is a medical device company providing solutions for patients with neuromuscular conditions.

CVRx

Tactile Medical

Crunchbase Website Twitter Facebook Linkedin

Tactile Medical develops medical devices that support the treatment of edema and vascular diseases at home.

CVRx

Cogentix Medical

Crunchbase Website Twitter Facebook Linkedin

Cogentix Medical products have increased treatment efficiency and lowered patient risk.

CVRx

Torax Medical

Crunchbase Website Twitter Facebook Linkedin

Torax Medical develops an implantable device for the treatment of gastroesophageal reflux disease.

CVRx

Urotronic

Crunchbase Website Twitter Facebook Linkedin

A Minnesota based, medical device company, making an exciting innovation in urethral stricture treatment.

CVRx

Venture Med Group

Crunchbase Website Twitter Facebook Linkedin

VMG designs, develops which enable interventionalists to cost effectively treat peripheral artery diseases.

CVRx

Osprey Medical

Crunchbase Website Twitter Facebook Linkedin

Osprey Medical develops and commercializes its propriety CINCOR™ System designed for the prevention of contrast induced mephropathy.

CVRx

Imbio

Crunchbase Website Twitter Facebook Linkedin

Imbio develops medical imaging software solutions that save lives and reduce costs.

CVRx

Rotation Medical

Crunchbase Website Twitter Facebook Linkedin

Rotation Medical develops treatments for rotator cuff disease by reversing disease progression and restoring long-term shoulder function.

CVRx

Zyga Technology

Crunchbase Website Twitter Facebook Linkedin

Zyga Technology is a surgical solutions provider developing & commercializing medical devices for treating spine problems.

CVRx

Cryosa

Crunchbase Website Twitter Facebook Linkedin

CryOSA is a medical device company developing novel treatments for obstructive sleep apnea.

CVRx

ValenTx

Crunchbase Website Twitter Facebook Linkedin

ValenTx is a development-stage medical device company that focuses on minimally-invasive methods for the treatment of morbid obesity.

CVRx

Reprise Biomedical

Crunchbase Website Twitter Facebook Linkedin

Reprise Biomedical focuses on the development and commercialization of biological medical devices.

CVRx

Preceptis Medical

Crunchbase Website Twitter Facebook Linkedin

Preceptis Medical develops surgical tools that allow ear tube procedures to be performed with less pain.

CVRx

Tendyne Holdings

Crunchbase Website Twitter Facebook Linkedin

Tendyne is a medical device company developing a transcatheter aortic valve implantation system.

CVRx

Murata Vios

Crunchbase Website Twitter Facebook Linkedin

Murata Vios is a medical technology company developing wireless monitoring platform for intensive healthcare applications.

CVRx

SynerFuse

Crunchbase Website Twitter Facebook Linkedin

SynerFuse is a provider of traditional spine implants intended to offer long-term pain management without the use of addictive opioids

CVRx

Cardio Flow

Crunchbase Website Twitter Facebook Linkedin

Cardio Flow is an early-stage development company with a new approach to orbital atherectomy.

CVRx

Mardil Medical

Crunchbase Website Twitter Facebook Linkedin

Mardil Medical is a medical device company developing therapies for structural heart diseases and heart abnormalities.

CVRx

EmStop

Crunchbase Website Twitter Facebook Linkedin

EmStop engages in the medical devices business namely embolic protection devices.

CVRx

Vergent Bioscience

Crunchbase Website Twitter Facebook Linkedin

Vergent Bioscience is a biotech company leading the development of tumor-targeted molecular imaging molecules for cancer surgery.

CVRx

Interrad Medical

Crunchbase Website Twitter Facebook Linkedin

Interrad Medical develops innovative medical devices for use in minimally invasive interventional and surgical procedures.

CVRx

Vertebral Technologies

Crunchbase Website Twitter Facebook Linkedin

Vertebral Technologies is a medical device company that creates breakthrough implantable spinal devices.

CVRx

CoraVie Medical Inc.

Crunchbase Website Twitter Facebook Linkedin

Early stage med device co. developing a subcutaneous continuous blood pressure monitor for patients with uncontrolled hypertension.

CVRx

Autonomix Medical

Crunchbase Website Twitter Facebook Linkedin

Autonomix Medical is a developer of a novel technology designed to bring clarity to minimally invasive renal denervation.

CVRx

AUM Cardiovascular

Crunchbase Website Twitter Facebook Linkedin

AUM Cardiovascular is a medical device manufacturing company that specializes in the fields of biotechnology, medical, and healthcare.

CVRx

Surgical Information Sciences

Crunchbase Website Twitter Facebook Linkedin

Surgical Information Sciences is a healthcare Company.

CVRx

Novidan

Crunchbase Website Twitter Facebook Linkedin

Novidan is designs, engineers and source products for the hard of hearing patient.

CVRx

Stimdia Medical

Crunchbase Website Twitter Facebook Linkedin

Stimdia Medical is a developer of a lung pacing device intended to facilitate weaning patients from mechanical ventilation.

CVRx

Marblehead Medical

Crunchbase Website Twitter Facebook Linkedin

Marblehead Medical is a developer of device intended to optimize the efficacy of mechanical thrombectomy.

CVRx

Augustine Temperature Management

Crunchbase Website Twitter Facebook Linkedin

Augustine Temperature Management develops conductive fabric patient warming systems for surgical patients in the United States.

CVRx

B-MoGen Biotechnologies

Crunchbase Website Twitter Facebook Linkedin

B-MoGen Biotechnologies is a genome engineering startup out of Minneapolis, MN.

CVRx

SuperDimension

Crunchbase Website Twitter Facebook Linkedin

SuperDimension is a medical device company developing minimally invasive pulmonology devices for the treatment of distal lung disease.

CVRx

Nirva Medical

Crunchbase Website Twitter Facebook Linkedin

Nirva Medical is a medical device start up focusing on organ-specific therapy-delivery technology for various clinical applications.

CVRx

Cardia

Crunchbase Website Twitter Facebook Linkedin

Cardia is an innovative company engaged in developing, manufacturing and marketing transcatheter septal occluders.

CVRx

Skyline Medical Inc.

Crunchbase Website Twitter Facebook Linkedin

BioDrain Medical offers STREAMWAY System, a surgical fluid disposal device that eliminates exposure to blood and infectious fluids.

CVRx

NitriCap Medical

Crunchbase Website Twitter Facebook Linkedin

NitriCap Medical develops a single-use antimicrobial catheter insert device to fight catheter-related bloodstream infections.

CVRx

Celleration

Crunchbase Website Twitter Facebook Linkedin

Celleration is a medical device company developing and commercializing therapeutic ultrasound platforms.

CVRx

EmboMedics

Crunchbase Website Twitter Facebook Linkedin

EmboMedics develops and commercializes resorbable and drug-loaded embolization devices for the treatment of multiple indications.

CVRx

MetaModix

Crunchbase Website Twitter Facebook Linkedin

MetaModix manufactures surgical and medical instruments for the treatment of metabolic disease and Type II diabetes.

CVRx

Phraxis

Crunchbase Website Twitter Facebook Linkedin

Phraxis is a medical device company developing solutions for patients who need vascular access to enable hemodialysis.

CVRx

Smiths Medical

Crunchbase Website Twitter Facebook Linkedin

Smiths Medical is innovator of specialized medical technologies focusing on the medication delivery, vital care and safety devices.

CVRx

Pursuit Vascular

Crunchbase Website Twitter Facebook Linkedin

Pursuit Vascular is focused on developing innovative catheter infection reduction technologies.

CVRx

Peytant Solutions

Crunchbase Website Twitter Facebook Linkedin

Peytant Solutions is a regenerative medical device company.

CVRx

Radux Devices

Crunchbase Website Twitter Facebook Linkedin

Radux Devices develops medical devices that improve the procedural performance of physicians, healthcare professionals, and hospitals.

CVRx

RespirTech

Crunchbase Website Twitter Facebook Linkedin

RespirTech dedicated to improving the quality of life for those living with respiratory complications.

CVRx

St. Jude Medical

Crunchbase Website Twitter Facebook Linkedin

St. Jude Medical develops medical technology and services that focus on putting more control into the hands of those who treat cardiac,

CVRx

Chitogen

Crunchbase Website Twitter Facebook Linkedin

Chitogen is a medical device company designing, manufacturing, and selling topical hemostats and related wound care products.

CVRx

Caisson Interventional

Crunchbase Website Twitter Facebook Linkedin

Caisson Interventional is a privately held clinical-stage medical device company focused on the design.

CVRx

Uromedica

Crunchbase Website Twitter Facebook Linkedin

Uromedica is a medical device company developing an adjustable balloon device for stress urinary incontinence (SUI).

CVRx

Sterilucent

Crunchbase Website Twitter Facebook Linkedin

Sterilucent is a health care company that develops and markets vaporized (gas) hydrogen peroxide technology.

CVRx

SubioMed

Crunchbase Website Twitter Facebook Linkedin

SubioMed specializes in the invention and development of suspension biomechanics technology addressing gait and balance.

CVRx

Zurich Medical

Crunchbase Website Twitter Facebook Linkedin

Zurich Medical develops proprietary medical devices.

CVRx

Advanced Circulatory System

Crunchbase Website Twitter Facebook Linkedin

Advanced Circulatory System manufactures and markets intrathoracic pressure regulation products.

CVRx

AdrenaCard

Crunchbase Website Twitter Facebook Linkedin

AdrenaCard is a pharmaceutical company that combines proven, life-saving drugs with devices that make them easier to carry.

CVRx

UroCure

Crunchbase Website Twitter Facebook Linkedin

UroCure is a healthcare company that re-commercializes slings for female incontinence with IP re-acquired from AMS.

CVRx

Tiumed, LLC

Crunchbase Website Twitter Facebook Linkedin

Tiumed’s next-generation plasma technology platform addresses the critical gap in BPH surgery with improved effectiveness and efficiency.

CVRx

Egg Medical

Crunchbase Website Twitter Facebook Linkedin

Egg Medical is a medical device company that offers EGGNEST, a passive protection designed to drastically reduce scatter radiation exposure.

CVRx

HealtheMed

Crunchbase Website Twitter Facebook Linkedin

HealtheMed is a telemedicine company targeting Medicaid Special Needs Basic Care (SNBC) patients with medication adherence.

CVRx

Exostat Medical

Crunchbase Website Twitter Facebook Linkedin

Exostat Medical develops MicroStat Systems, a systemic monitoring device to measure carbon dioxide in the oral mucosa.

CVRx

InterValve

Crunchbase Website Twitter Facebook Linkedin

InterValve develops medical devices and technology for the catheter-based treatment of calcified aortic valve stenosis.

CVRx

NovoPulse

Crunchbase Website Twitter Facebook Linkedin

NovoPulse is a thermally assisted electrical stimulation device designed for pain management and treatment of osteoarthritis.

CVRx

OrthoCor Medical

Crunchbase Website Twitter Facebook Linkedin

OrthoCor Medical develops and delivers medical devices for joint pain.

CVRx

GT Urological

Crunchbase Website Twitter Facebook Linkedin

GT Urological, LLC develops, manufactures, distributes, and markets medical devices for the urinary incontinence market.

CVRx

Levity Products

Crunchbase Website Twitter Facebook Linkedin

Levity Products is provides health care services.

CVRx

Wound Care Technologies

Crunchbase Website Twitter Facebook Linkedin

Wound Care Technologies, a medical technology company, develops and markets external tissue expansion devices for the wound care market.

CVRx

Prospex Medical

Crunchbase Website Twitter Facebook Linkedin

Prospex Medical is a medical device incubator focused on innovating and incubating novel medical technologies.

CVRx

MFr Technologies

Crunchbase Website Twitter Facebook Linkedin

MFr Technologies is a health care company.

CVRx

Medafor

Crunchbase Website Twitter Facebook Linkedin

Medafor develops novel hemostatic technology and absorbable hemostats called MPH(R), which accelerates the normal blood clotting process.

CVRx

Vital Images

Crunchbase Website Twitter Facebook Linkedin

Vital Images, is a rovider of enterprise-wide advanced visualization and analysis software solutions.

CVRx

Circle Biologics

Crunchbase Website Twitter Facebook Linkedin

Circle Biologics develops and markets biologic treatments and intra-operative biologic material management systems.

CVRx

Dgimed Ortho

Crunchbase Website Twitter Facebook Linkedin

DGIMed Ortho is an early-stage orthopedic trauma company that develops an intramedullary nailing system and distal targeting device.

CVRx

Patterson Companies

Crunchbase Website Twitter Facebook Linkedin

Patterson Companies is an industry-leading specialty distributor serving the dental, veterinary and rehabilitation supply markets.

CVRx

CloSys

Crunchbase Website Twitter Facebook Linkedin

CloSys develops hemostatic devices used for rapid vascular closure for anti-coagulated patients.

CVRx

Aurora Concussion Therapy Systems

Crunchbase Website Twitter Facebook Linkedin

Aurora Concussion Therapy Systems is developing a non-invasive therapy for concussions (mild traumatic brain injury or mTBI).

Written by Warren Tesla

My name is Tesla and I am the pseudonym used by The Stratup Pill's broad writing team.

About me: Founder, CEO, CTO, CFO, CMO, CISO, Director, Head of the Board, Head of the oversight board, Executive, Legal Council, Head of Hiring, HR Manager, Consultant.

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